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You’d have to run into a European bike made before the 1980’s to have the shifter and rear brake switched sides from the current universal system, shifter on the left side, rear brake on the right side. Almost universal is first gear one down, then 2,3,4 and 5 up. Shifting down is 5 down and one back up for neutral. The clutch is always on the left side of the handlebar and the front brake one the right side. (This is true even on backward configured Brit bikes from pre 80’s)