Jay, Israel will use nuclear weapons if it sees no other solution. Read: http://en.wikipedia.org/wiki/Nuclear_weapons_and_Israel Israeli nuclear arsenal vary between 75 and 400 nuclear warheads.
With that many nuclear warheads there is no country in the world that will be able to stop them if they need to use them.
Here are some facts of how many nuclear bombs countries have, https://www.armscontrol.org/factsheets/Nuclearweaponswhohaswhat Israel: Between 75 to 200 nuclear warheads on this website.
So how many do they have well more the 75 for sure. So if they have 100 is that enough to destroy all the middle east? YES!